BDBM50459352 CHEMBL4217435::US10751335, Example 15
SMILES Clc1cc2[nH]c(=O)n(C3CCN(Cc4ccc(Br)cc4)CC3)c2cc1Cl
InChI Key InChIKey=MKPRNBUMJPGQCS-UHFFFAOYSA-N
Data 10 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50459352
Affinity DataEC50: 92nMAssay Description:he CisBio cAMP cell based assay kit that uses HTRF technology was utilized to assess MOR-mediated inhibition of cAMP. Assays were performed according...More data for this Ligand-Target Pair
Affinity DataEC50: 129nMAssay Description:A standard [35S]GTPγS binding assay in membranes prepared from CHO cells expressing the human MOR was performed in a concentration response mann...More data for this Ligand-Target Pair
Affinity DataEC50: 144nMAssay Description:A standard [35S]GTPγS binding assay in membranes prepared from CHO cells expressing the human MOR was performed in a concentration response mann...More data for this Ligand-Target Pair
Affinity DataEC50: 149nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by ...More data for this Ligand-Target Pair
Affinity DataEC50: 155nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membranes after 1 hr by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 350nMAssay Description:A standard [35S]GTPγS binding assay in membranes prepared from CHO cells expressing the human MOR was performed in a concentration response mann...More data for this Ligand-Target Pair
Affinity DataEC50: 501nMAssay Description:Inhibition of human mu-opioid receptor assessed as reduction in intracellular cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Inhibition of human mu-opioid receptor assessed as increase in beta arrestin 2 recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human mu opioid receptor expressed in human USOS-beta-arrestin-hMOR-PathHunter cells incubated for 90 mins by beta-arrestin-2 enz...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human mu opioid receptor expressed in human U2OS cells co-transfected with beta-arrestin-2 assessed as increase in beta-arrestin-...More data for this Ligand-Target Pair