BDBM50459444 CHEMBL4217068

SMILES Cc1cc(Cn2c(nc3c(cc(Cl)cc23)-c2cccc(c2)C(F)(F)F)N2CCNCC2)cc(C)c1F

InChI Key InChIKey=NTXSFWFCXIKVPT-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50459444   

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50459444(CHEMBL4217068)
Affinity DataKd:  670nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli by fluorescent probe ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed