BDBM50459645 CHEMBL4213030

SMILES Cc1ncccc1-c1cc(F)cc(c1)N1C[C@@H](CC1=O)N1CCN(CC1)c1ncccn1

InChI Key InChIKey=KRTLYJDCOZBDAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50459645   

TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50459645(CHEMBL4213030)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of His-tagged human MAGL expressed in Escherichia coli BL21(DE3) assessed as reduction in arachidonic acid production from 2-arachidonoylg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50459645(CHEMBL4213030)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human FAAH expressed in CHOK1 cells using AMCAA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed