BDBM50459697 CHEMBL4214693

SMILES COc1c(ccc2OC(C)(C)C=Cc12)C(=O)Cc1cccc(F)c1

InChI Key InChIKey=RJZBQWUGKKHVDY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50459697   

TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50459697(CHEMBL4214693)
Affinity DataIC50: 360nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed