BDBM50459698 CHEMBL4214799::US12006283, Example 13

SMILES CC(C(=O)c1ccc(cc1)N1CCCCC1)c1ccccc1F

InChI Key InChIKey=UQILSDDZPHWQBW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50459698   

TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

US Patent
LigandPNGBDBM50459698(CHEMBL4214799 | US12006283, Example 13)
Affinity DataIC50: 2.06E+3nMAssay Description:The experiment was performed in order to evaluate inhibitory activity against angiogenesis of the compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2024
Entry Details
US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Seoul National University

US Patent
LigandPNGBDBM50459698(CHEMBL4214799 | US12006283, Example 13)
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of HIF-1alpha in human HRE-A549 cells pre-incubated for 1 hr before exposure to hypoxia for 24 hrs by HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed