BDBM50459913 CHEMBL4227623

SMILES CC[C@H](NC(=O)COCCCOCCCCOCCCOc1ccc(Nc2ncc(Br)c(NCCCN(C)C(=O)C3CCC3)n2)cc1)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C

InChI Key InChIKey=PAVSYJSRMMUDDB-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50459913   

TargetElongin-B/Elongin-C/Hypoxia-inducible factor 1-alpha/von Hippel-Lindau disease tumor suppressor(Human)
Arvinas

Curated by ChEMBL

LigandBDBM50459913(CHEMBL4227623)Copy SMILESCopy InChI

Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details Article
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