BDBM50460037 CHEMBL4228766

SMILES C(CN1CCCC1)Oc1ccc2Nc3nccc(n3)-c3ccc(OC\C=C\COCc1c2)o3

InChI Key InChIKey=WLSNEPFUAQBBFD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50460037   

TargetTyrosine-protein kinase JAK2(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460037(CHEMBL4228766)
Affinity DataIC50: 46nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460037(CHEMBL4228766)
Affinity DataIC50: 62nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460037(CHEMBL4228766)
Affinity DataIC50: 69nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460037(CHEMBL4228766)
Affinity DataIC50: 230nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460037(CHEMBL4228766)
Affinity DataIC50: 277nMAssay Description:Inhibition of CSF1R signaling in human PBMC assessed as reduction in M-CSF-induced differentiation after 7 days by immunostaining analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed