BDBM50460045 CHEMBL4226926

SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1nc2c(C)nc(N)nc2n(C)c1=O

InChI Key InChIKey=VABHZMQJUZDGNK-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50460045   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Peking Union Medical College

Curated by ChEMBL

LigandBDBM50460045(CHEMBL4226926)Copy SMILESCopy InChI

Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PI3Kalpha expressed in baculovirus expression system using PIP2 as substrate measured after 1 h...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details Article
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