BDBM50460055 CHEMBL4227858

SMILES CCC(=O)Nc1nc(C)c2cc(sc2n1)-c1cnc(OC)c(NS(=O)(=O)c2ccc(F)cc2F)c1

InChI Key InChIKey=PFGIZSASYPLVGU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50460055   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Peking Union Medical College

Curated by ChEMBL

LigandBDBM50460055(CHEMBL4227858)Copy SMILESCopy InChI

Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PI3Kalpha expressed in baculovirus expression system using PIP2 as substrate measured after 1 h...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL