BDBM50460199 CHEMBL4225876

SMILES Cc1ccc2oc(nc2c1)C(\Cc1ccc(F)cc1)=N\O

InChI Key InChIKey=NCGJNSAWMBTTKV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50460199   

TargetXanthine dehydrogenase/oxidase(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50460199(CHEMBL4225876)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 1 to 5 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50460199(CHEMBL4225876)
Affinity DataIC50: 4.57E+4nMAssay Description:Inhibition of human TLR4 signaling expressed in HEK-Blue cells co-expressing MD2/CD14 assessed as reduction in LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed