BDBM50460212 CHEMBL4227524

SMILES O\N=C(/Cc1ccccc1)c1nc2ccc(Cl)cc2o1

InChI Key InChIKey=VENAVMCFNBAOAL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50460212   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50460212(CHEMBL4227524)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of NLRP3 inflammasome in human THP1 cells assessed as reduction in MSU-induced IL-1beta production preincubated for 1 hr followed by MSU s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50460212(CHEMBL4227524)
Affinity DataIC50: 2.69E+4nMAssay Description:Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 1 to 5 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed