BDBM50460324 CHEMBL4226885

SMILES CC(C)OC(=O)N1CCC2(CC(CCCOc3ccc(C(=O)N4CCC4)c(F)c3)C2)CC1

InChI Key InChIKey=UNBGRCPLGVGKJS-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50460324   

TargetGlucose-dependent insulinotropic receptor(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50460324(CHEMBL4226885)
Affinity DataEC50:  34nMAssay Description:Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50460324(CHEMBL4226885)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50460324(CHEMBL4226885)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed