BDBM50460574 CHEMBL4225922

SMILES CC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(c(C)c1-c1cccc(c1)-c1ccccc1)-c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=FKJPDOUATJOANE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50460574   

TargetGlucagon receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50460574(CHEMBL4225922)
Affinity DataIC50: 370nMAssay Description:Displacement of [125I]-glucagon from wild type human glucagon receptor expressed in CHOK1 cells after 3 hrs by micro beta scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50460574(CHEMBL4225922)
Affinity DataIC50: 450nMAssay Description:Antagonist activity at human glucagon receptor expressed in HEK293T cells assessed as inhibition of glucagon-induced cAMP accumulation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed