BDBM50460584 CHEMBL4227967

SMILES Cc1c(nn(Cc2ccc(cc2)C(=O)NCCC(O)=O)c1-c1cccc2ccccc12)-c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=JKZCNWPHJWAAHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50460584   

TargetGlucagon receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50460584(CHEMBL4227967)
Affinity DataIC50: 2.38E+3nMAssay Description:Antagonist activity at human glucagon receptor expressed in HEK293T cells assessed as inhibition of glucagon-induced cAMP accumulation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50460584(CHEMBL4227967)
Affinity DataIC50: 2.79E+3nMAssay Description:Displacement of [125I]-glucagon from wild type human glucagon receptor expressed in CHOK1 cells after 3 hrs by micro beta scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed