BDBM50460793 CHEMBL4225507

SMILES CCNC(=O)c1cc2c(nc(N)nc2s1)-c1cccc(OCCCCCn2cc(cn2)-c2ncnc3[nH]ccc23)c1

InChI Key InChIKey=GWNLNWBFGLYUDU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50460793   

TargetTyrosine-protein kinase JAK2(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50460793(CHEMBL4225507)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50460793(CHEMBL4225507)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of geldanamycin-based probe binding to HSP90 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed