BDBM50460794 CHEMBL4228653

SMILES CCNC(=O)c1cc2c(nc(N)nc2s1)-c1cccc(OCCCCCCOc2ccc(Nc3nc(-c4cnn(CCCCCCC(=O)NO)c4)c4cc[nH]c4n3)cc2)c1

InChI Key InChIKey=AAEICMCECKWAAC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50460794   

TargetHistone deacetylase 6(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50460794(CHEMBL4228653)
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate after 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50460794(CHEMBL4228653)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate after 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50460794(CHEMBL4228653)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50460794(CHEMBL4228653)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HSP90alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed