BDBM50460913 CHEMBL138623

SMILES CCN(CC)Cc1cccc(Nc2ccnc3cc(Cl)ccc23)c1

InChI Key InChIKey=QPUCYHAMXCCZFO-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50460913   

TargetAmyloid-beta precursor protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50460913(CHEMBL138623)
Affinity DataIC50: 1.04E+4nMAssay Description:Modulation of human wild-type APP695 expressed in SH-SY5Y cells assessed as inhibition of amyloid beta (1 to 42 residues) production measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50460913(CHEMBL138623)
Affinity DataIC50: 4.50E+3nMAssay Description:Modulation of human wild-type APP695 expressed in SH-SY5Y cells assessed as inhibition of amyloid beta (1 to 40 residues) production measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50460913(CHEMBL138623)
Affinity DataEC50:  1.16E+5nMAssay Description:Agonist activity at Gal4-fused human Nurr1 LBD expressed in HEK293T cells co-expressing firefly luciferase assessed as luciferase activity incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed