BDBM50460915 CHEMBL4227472

SMILES Clc1ccc2c(Nc3cc(CN4CCOCC4)cc(NCCN4CCCCC4)c3)ccnc2c1

InChI Key InChIKey=YPLICUFDFKHGBN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50460915   

TargetAmyloid-beta precursor protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50460915(CHEMBL4227472)
Affinity DataIC50: 4.90E+3nMAssay Description:Modulation of human wild-type APP695 expressed in SH-SY5Y cells assessed as inhibition of amyloid beta (1 to 42 residues) production measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50460915(CHEMBL4227472)
Affinity DataIC50: 2.50E+3nMAssay Description:Modulation of human wild-type APP695 expressed in SH-SY5Y cells assessed as inhibition of amyloid beta (1 to 40 residues) production measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed