BDBM50460931 CHEMBL94521

SMILES Clc1ccc2c(Nc3cc(CN4CCOCC4)cc(NC(=O)CN4CCCCC4)c3)ccnc2c1

InChI Key InChIKey=UENVABGRVVRAKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50460931   

TargetAmyloid-beta precursor protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50460931(CHEMBL94521)
Affinity DataIC50: 7.10E+3nMAssay Description:Modulation of human wild-type APP695 expressed in SH-SY5Y cells assessed as inhibition of amyloid beta (1 to 42 residues) production measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50460931(CHEMBL94521)
Affinity DataIC50: 3.10E+3nMAssay Description:Modulation of human wild-type APP695 expressed in SH-SY5Y cells assessed as inhibition of amyloid beta (1 to 40 residues) production measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed