BDBM50461301 CHEMBL4227475

SMILES CC(C)[C@H]1c2ccc(F)cc2CC[C@@]1(CCN(C)CCCc1nc2ccccc2[nH]1)OC(=O)C1CC1

InChI Key InChIKey=VHHVPDKNKPNKHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50461301   

TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50461301(CHEMBL4227475)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50461301(CHEMBL4227475)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed