BDBM50461372 CHEMBL4225142

SMILES COc1ncc(cc1NS(C)(=O)=O)-c1cc(NC(=O)c2coc(CN3CCN(CC3)C(C)C)n2)c2cnn(C)c2n1

InChI Key InChIKey=CQCTXDAVKKVUQO-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50461372   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Astellas Pharma

Curated by ChEMBL

LigandBDBM50461372(CHEMBL4225142)Copy SMILESCopy InChI

Affinity DataIC50: 8.40nMAssay Description:Inhibition of recombinant human full length N-terminal His6-tagged PI3K p110delta/untagged recombinant full length human p85alpha expressed in baculo...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/17/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Astellas Pharma

Curated by ChEMBL

LigandBDBM50461372(CHEMBL4225142)Copy SMILESCopy InChI

Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged full length PI3K p110alpha/untagged recombinant full length human p85alpha expressed in baculo...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/17/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL