BDBM50461447 CHEMBL4228016

SMILES CCC(=O)[C@H](C[C@H](C)C(Cl)(Cl)Cl)NC(=O)\C=C\[C@H](C)C(Cl)(Cl)Cl

InChI Key InChIKey=ZQVVKTNITFQVMX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50461447   

TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461447(CHEMBL4228016)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461447(CHEMBL4228016)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461447(CHEMBL4228016)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of African green monkey SOAT1 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461447(CHEMBL4228016)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of African green monkey SOAT2 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed