BDBM50461476 CHEMBL4228400

SMILES Nc1nc2cc(cc(-c3ccncc3)c2c(=O)n1CC1CCCO1)-c1ccccc1

InChI Key InChIKey=XDELNVNPKHUFGK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50461476   

TargetPlasmepsin I(malaria parasite P. falciparum)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50461476(CHEMBL4228400)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-1 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPlasmepsin IV [1-448](malaria parasite P. falciparum)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50461476(CHEMBL4228400)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 4 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCathepsin D(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50461476(CHEMBL4228400)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50461476(CHEMBL4228400)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed