BDBM50461680 CHEMBL4226439

SMILES [H][C@@]12C[C@]3([H])C[C@@H](CCC3[C@H](\C=C\c3ccc(cn3)-c3cccc(F)c3)[C@]1([H])[C@@H](C)OC2=O)NC(=O)OCC

InChI Key InChIKey=ZBGXUVOIWDMMJE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50461680   

TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50461680(CHEMBL4226439)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50461680(CHEMBL4226439)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed