BDBM50461684 CHEMBL4226980

SMILES Fc1ccc(C[C@H](NC(=O)Nc2ccc3c(CN4CCCC4)nn(Cc4c(Cl)cccc4Cl)c3c2)C(=O)N[C@@H](CCNC(=O)CCC#C)C(=O)NCc2ccccc2)cc1F

InChI Key InChIKey=ZECAITLWVXGIBW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50461684   

TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50461684(CHEMBL4226980)
Affinity DataIC50: 290nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50461684(CHEMBL4226980)
Affinity DataIC50: 316nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed