BDBM50462026 CHEMBL4229177

SMILES Cc1nc2c([nH]1)C(=O)C(Cl)=C(Nc1cc(F)cc(F)c1)C2=O

InChI Key InChIKey=ONCRMOXJCSLZOT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50462026   

TargetGenome polyprotein(Coxsackievirus B3 (strain Nancy))
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50462026(CHEMBL4229177)
Affinity DataIC50: 900nMAssay Description:Inhibition of human coxsackievirus B3 protease 3C expressed in Escherichia coli (BL21) using fluorogenic-Dabcyl-KEALFQGPPQFE-Edans as substrate after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGenome polyprotein(HRV-14)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50462026(CHEMBL4229177)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of recombinant human rhinovirus protease 3C using fluorogenic-Dabcyl-KTSAVLQSGFRKME-Edan as substrate after 5 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed