BDBM50462032 CHEBI:3720::CHEMBL560739::US11590142, Compound Cisapride

SMILES CO[C@H]1CN(CCCOc2ccc(F)cc2)CC[C@H]1NC(=O)c1cc(Cl)c(N)cc1OC

InChI Key InChIKey=DCSUBABJRXZOMT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50462032   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50462032(CHEMBL560739 | CHEBI:3720 | US11590142, Compound C...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50462032(CHEMBL560739 | CHEBI:3720 | US11590142, Compound C...)
Affinity DataIC50: 150nMAssay Description:Compounds were solubilised to 100 mM in DMSO before dilution in HBPS to 300 μM. 6-Point concentration-response curves were generated using 3.16-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent