BDBM50462285 CHEMBL4241176

SMILES CC(=O)NCc1cccc(OC[C@@H](O)CNCCc2ccc(NS(=O)(=O)Nc3ccccc3)cc2)c1

InChI Key InChIKey=KAYOMTGFORONIU-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50462285   

TargetBeta-3 adrenergic receptor(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50462285(CHEMBL4241176)
Affinity DataEC50:  3.40nMAssay Description:Antagonist activity at human beta3 adrenergic receptor expressed in HEK293 cells co-expressing Galpha16 assessed as inhibition of isoproterenol-induc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50462285(CHEMBL4241176)
Affinity DataEC50:  224nMAssay Description:Antagonist activity at human beta1 adrenergic receptor expressed in HEK293 cells co-expressing Galpha16 assessed as inhibition of isoproterenol-induc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50462285(CHEMBL4241176)
Affinity DataEC50:  8.43E+3nMAssay Description:Antagonist activity at human beta2 adrenergic receptor expressed in HEK293 cells co-expressing Galpha16 assessed as inhibition of isoproterenol-induc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed