BDBM50462373 CHEMBL4249147

SMILES COc1ccc2c(OCc3nnc4sc(nn34)-c3cnn(C)c3)ccnc2c1

InChI Key InChIKey=GXUPYZJWBBTOOA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50462373   

TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50462373(CHEMBL4249147)
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-tagged human c-MET preincubated for 20 mins followed by [33P]-ATP addition and measured after 2 hrs by Hot-Spot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50462373(CHEMBL4249147)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of GST-tagged human FLT3 preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-Spot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed