BDBM50462555 CHEMBL4240266

SMILES CC(C)CCN(C(=O)CCl)c1cc(cc(c1)C(F)(F)F)C(=O)NCc1cccc(c1)[N+]([O-])=O

InChI Key InChIKey=UGFIPIXTQKVDIU-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50462555   

TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462555(CHEMBL4240266)
Affinity DataIC50: 180nMAssay Description:Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate preincubated for 1 hr followed by substrate and SAM addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462555(CHEMBL4240266)
Affinity DataIC50: 350nMAssay Description:Inhibition of SAH-rhodamine binding to NNMT in human 786-O cell soluble proteomic lysate preincubated for 1 hr followed by SAH-rhodamine addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462555(CHEMBL4240266)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate pretreated for 1 hr at 3 mins post 10 uM SAM addition followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462555(CHEMBL4240266)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate pretreated for 1 hr at 3 mins post 20 uM SAM addition followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462555(CHEMBL4240266)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate pretreated for 1 hr at 3 mins post 40 uM SAM addition followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462555(CHEMBL4240266)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate pretreated for 1 hr at 3 mins post 80 uM SAM addition followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462555(CHEMBL4240266)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate pretreated for 1 hr at 3 mins post 160 uM SAM addition followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed