BDBM50462560 CHEMBL4238535

SMILES O=C(CCl)N(CCc1ccccc1)c3cc(C(=O)Nc2cccnc2Cl)cc(C(F)(F)F)c3

InChI Key InChIKey=UPPOSJMSZZQZTP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50462560   

TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462560BDBM50462560(CHEMBL4238535)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate preincubated for 1 hr followed by substrate and SAM addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462560BDBM50462560(CHEMBL4238535)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of SAH-rhodamine binding to NNMT in human 786-O cell soluble proteomic lysate preincubated for 1 hr followed by SAH-rhodamine addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed