BDBM50463232 CHEMBL4251370

SMILES O[C@H](CNc1nc(nc(n1)N1CCOCC1)C#N)c1ccccc1

InChI Key InChIKey=DLVIQZHJLFTHNM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50463232   

TargetCathepsin K(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50463232(CHEMBL4251370)
Affinity DataIC50: 700nMAssay Description:Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCathepsin S(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50463232(CHEMBL4251370)
Affinity DataIC50: 800nMAssay Description:Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCathepsin B(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50463232(CHEMBL4251370)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human cathepsin B using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50463232(CHEMBL4251370)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed