BDBM50463546 CHEMBL4245382

SMILES ONC(=O)[C@@H]1C[C@@H](CN1S(=O)(=O)c1ccc(Oc2ccccc2)cc1)NC(=O)c1ccc2no[n+]([O-])c2c1

InChI Key InChIKey=BEESELNNLKKWAG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50463546   

TargetMatrix metalloproteinase-9(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50463546(CHEMBL4245382)
Affinity DataIC50: 162nMAssay Description:Inhibition of recombinant human MMP9 (Phe107 to Pro449 residues) expressed in Escherichia coli preincubated for 45 mins followed by Mea-Pro-Leu-Gly-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50463546(CHEMBL4245382)
Affinity DataIC50: 102nMAssay Description:Inhibition of recombinant human MMP2 catalytic domain (Tyr110 to Asp452 residues) preincubated for 45 mins followed by Mea-Pro-Leu-Gly-Leu-Dap(Dnp)-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed