BDBM50463547 CHEMBL4249544

SMILES COc1ccc(\C=C\C(=O)N2C[C@H](C[C@H]2C(=O)NO)NC(=O)c2ccc3no[n+]([O-])c3c2)cc1OC

InChI Key InChIKey=NTWDIGYKYNMIHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50463547   

Target72 kDa type IV collagenase(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50463547(CHEMBL4249544)
Affinity DataIC50: 345nMAssay Description:Inhibition of recombinant human MMP2 catalytic domain (Tyr110 to Asp452 residues) preincubated for 45 mins followed by Mea-Pro-Leu-Gly-Leu-Dap(Dnp)-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50463547(CHEMBL4249544)
Affinity DataIC50: 388nMAssay Description:Inhibition of recombinant human MMP9 (Phe107 to Pro449 residues) expressed in Escherichia coli preincubated for 45 mins followed by Mea-Pro-Leu-Gly-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed