BDBM50463682 CHEMBL4246259

SMILES CCc1c2Cn3c(cc4c(COC(=O)[C@]4(O)CC)c3=O)-c2nc2ccc(OC(=O)N3CCN(CC3)C(=O)CCCCCCC(=O)NO)cc12

InChI Key InChIKey=KRJLWDXXPHEJQA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50463682   

TargetHistone deacetylase 1(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50463682(CHEMBL4246259)
Affinity DataIC50: 5.57E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in baculovirus infected High5 insect cells using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50463682(CHEMBL4246259)
Affinity DataIC50: 9.32E+3nMAssay Description:Inhibition of recombinant human HDAC3 expressed in baculovirus infected High5 insect cells using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50463682(CHEMBL4246259)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of recombinant human HDAC6 expressed in baculovirus infected High5 insect cells using Boc-Lys (epsilon-acetyl)-AMC as substrate after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed