BDBM50463688 CHEMBL4238745

SMILES CCc1c2Cn3c(cc4c(COC(=O)[C@@]4(CC)OC(=O)CCCCCCC(O)=O)c3=O)-c2nc2ccc(O)cc12

InChI Key InChIKey=LAYBFQIOZFATTJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50463688   

TargetHistone deacetylase 6(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50463688(CHEMBL4238745)
Affinity DataIC50: 6.94E+3nMAssay Description:Inhibition of recombinant human HDAC6 expressed in baculovirus infected High5 insect cells using Boc-Lys (epsilon-acetyl)-AMC as substrate after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50463688(CHEMBL4238745)
Affinity DataIC50: 2.71E+4nMAssay Description:Inhibition of recombinant human HDAC1 expressed in baculovirus infected High5 insect cells using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50463688(CHEMBL4238745)
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of recombinant human HDAC3 expressed in baculovirus infected High5 insect cells using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed