BDBM50464531 CHEMBL4288220

SMILES CCC(CCCC(=O)Nc1ccccc1)CCC(=O)NO

InChI Key InChIKey=SAZYUSNRLANPTC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50464531   

TargetHistone deacetylase 8(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464531(CHEMBL4288220)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464531(CHEMBL4288220)
Affinity DataIC50: 160nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464531(CHEMBL4288220)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of HDAC1 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464531(CHEMBL4288220)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of HDAC2 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464531(CHEMBL4288220)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of HDAC3 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464531(CHEMBL4288220)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of HDAC in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 35 mins by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed