BDBM50464537 CHEMBL4280303

SMILES CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccc(O)cc4c(\C=N\OCCCCCC(=O)NCCSSCCNC(=O)C(\Cc4ccc(O)c(Br)c4)=N/O)c3Cn1c2=O

InChI Key InChIKey=PDRHOJIVDMXSPA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50464537   

TargetPolyamine deacetylase HDAC10(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50464537(CHEMBL4280303)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of HDAC10 (unknown origin) using RHKK(Ac)AMC as substrate after 1 to 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50464537(CHEMBL4280303)
Affinity DataIC50: 252nMAssay Description:Inhibition of HDAC1 (unknown origin) using RHKK(Ac)AMC as substrate after 1 to 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50464537(CHEMBL4280303)
Affinity DataIC50: 409nMAssay Description:Inhibition of HDAC2 (unknown origin) using RHKK(Ac)AMC as substrate after 1 to 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50464537(CHEMBL4280303)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate after 1 to 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed