BDBM50464546 CHEMBL4291295

SMILES Nc1ccccc1NC(=O)c1ccc(CSC(=S)N2CCc3ccccc3C2)cc1

InChI Key InChIKey=XLMWCZDPVMJXAC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50464546   

TargetHistone deacetylase 1(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50464546(CHEMBL4291295)
Affinity DataIC50: 2.57E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys-Green as substrate preincubated for 5 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50464546(CHEMBL4291295)
Affinity DataIC50: 3.23E+3nMAssay Description:Inhibition of human recombinant HDAC2 using Fluor de Lys-Green as substrate preincubated for 5 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50464546(CHEMBL4291295)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant HDAC6 using Fluor de Lys-Green as substrate preincubated for 5 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed