BDBM50464929 CHEMBL4281045

SMILES Cn1c(nc2c(cc(F)cc12)C(N)=O)-c1cc2CCNCc2s1

InChI Key InChIKey=MHEGXLWYODUJMQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50464929   

TargetPoly [ADP-ribose] polymerase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50464929(CHEMBL4281045)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of NAD+ by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50464929(CHEMBL4281045)
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant human PARP2 using histone as substrate after 1.5 hr in presence of NAD+ by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed