BDBM50465002 CHEMBL4280157::US12441690, Example 4

SMILES CSc1ncc(C(=O)NCCc2c[nH]c3ccccc23)c(n1)N1CCOCC1

InChI Key InChIKey=DRHWILWCGVVNNS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465002   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Seoul National University R&D Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50465002BDBM50465002(CHEMBL4280157 | US12441690, Example 4)
Affinity DataIC50: 166nMAssay Description:In order to evaluate the PDE4B inhibitory activity of the compounds according to the present invention, the following experiment was performed using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2026
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Seoul National University R&D Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50465002BDBM50465002(CHEMBL4280157 | US12441690, Example 4)
Affinity DataIC50: 166nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged PDE4B1 expressed in baculovirus infected Sf9 cells using cAMP as substrate after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed