BDBM50465068 CHEMBL4287163

SMILES NS(=O)(=O)c1ccc(cc1)[C@H]1[C@H](c2noc(n2)-c2ccccc2)C1(F)F

InChI Key InChIKey=JRGDEDZRXPVNBQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50465068   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50465068(CHEMBL4287163)
Affinity DataEC50:  83nMAssay Description:Positive allosteric modulation of human alpha 7 nAChR expressed in HEK cells co-expressing human RIC3 assessed as increase in acetylcholine-induced c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed