BDBM50465086 CHEMBL4286227

SMILES COc1ccc2c(NC3CCN(Cc4ccccc4)CC3)nc(NCCNC(=O)CCCCCCC(=O)NO)nc2c1

InChI Key InChIKey=JIVWNYWADHBBGR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50465086   

TargetHistone deacetylase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465086(CHEMBL4286227)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of HDAC in human HeLa cells using Boc-K(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465086(CHEMBL4286227)
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibition of HDAC in human K562 cells using Boc-K(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465086(CHEMBL4286227)
Affinity DataIC50: 3.78E+4nMAssay Description:Inhibition of G9a in human MDA-MB-231 cells assessed as reduction in H3K9me2 level after 2 days by immunofluorescence in-cell western analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465086(CHEMBL4286227)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC in human A549 cells using Boc-K(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed