BDBM50465147 CHEMBL4289739

SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1Cc2ccc(O)c(CC=CCCCCCCC(=O)N[C@@H](CCCCN)C(=O)N3CCC[C@H]3C(=O)N1)c2)C(=O)N[C@@H](CC(C)C)C(O)=O

InChI Key InChIKey=PJDKVHXZLHUPET-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50465147   

TargetNeurotensin receptor type 1(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50465147(CHEMBL4289739)
Affinity DataEC50:  166nMAssay Description:Agonist activity at Galphaq-Rluc2/Gbeta1/GFP10-Ggamma1 fused human NTS1 expressed in CHO-K1 cells assessed as Galphaq activation after 5 mins by BRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50465147(CHEMBL4289739)
Affinity DataIC50: 400nMAssay Description:Displacement of 125I-[Tyr3]-NT from human NTS1 receptor expressed in CHO-K1 cell membranes after 60 mins by gamma-counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
University of Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50465147(CHEMBL4289739)
Affinity DataEC50:  1.37E+3nMAssay Description:Agonist activity at GFP10-tagged human NTS1 expressed in CHO-K1 cells assessed as Rluc2-fused beta-arrestin2 recruitment after 20 mins by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed