BDBM50465291 CHEMBL4277571

SMILES COc1ccc(cc1)S(=O)(=O)Nc1cc(cnc1OC)-c1ccc2nccc(=O)n2c1

InChI Key InChIKey=HWMJJIJRAKNKJM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465291   

LigandPNGBDBM50465291(CHEMBL4277571)
Affinity DataIC50: 54nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465291(CHEMBL4277571)
Affinity DataIC50: 138nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed