BDBM50465374 CHEMBL4287869

SMILES CC1CC(CN(CC2CCN(C)C2)C1)c1ccc(C#N)c2ncccc12

InChI Key InChIKey=FDVMJVKEBUYLKY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50465374   

TargetToll-like receptor 7(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465374(CHEMBL4287869)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at TLR7 in HEK cells assessed as decrease in R848-induced NF-kappaB activation incubated for 30 mins followed by R848 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed