BDBM50465380 CHEMBL4283433

SMILES [H][C@@]12CNC[C@]1([H])[C@H]2CC(=O)N1C[C@H](C)C[C@H](C1)c1ccc(C#N)c2ncccc12

InChI Key InChIKey=AGOUBOOUAXHNJI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50465380   

TargetToll-like receptor 7(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465380(CHEMBL4283433)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at TLR7 in HEK cells assessed as decrease in R848-induced NF-kappaB activation incubated for 30 mins followed by R848 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed