BDBM50465398 CHEMBL4277863

SMILES Nc1ccccc1NC(=O)c1ccc(cn1)C(=O)NCCNc1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O

InChI Key InChIKey=AHNAIFAKGFYBHO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465398   

TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465398(CHEMBL4277863)
Affinity DataIC50: 604nMAssay Description:Inhibition of recombinant human full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465398(CHEMBL4277863)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human GST-tagged IDO1 (1 to 404 residues) using D-Tryptophan as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed