BDBM50465519 CHEMBL4286869

SMILES COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)N1CCNCC1

InChI Key InChIKey=RTOGLBGALXDBQH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50465519   

TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50465519(CHEMBL4286869)Copy SMILESCopy InChI

Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of NLRP3 in mouse J774A.1 cells assessed as reduction in LPS-stimulated IL-1beta levels pre-incubated with LPS for 4.5 hrs followed by inc...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/18/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL