BDBM50465674 CHEMBL4294946

SMILES NS(=O)(=O)c1ccc(O)c(NC(=O)Nc2ccccc2[N+]([O-])=O)c1

InChI Key InChIKey=ROMKHYLOEFSRJQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50465674   

TargetCarbonic anhydrase 9(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50465674(CHEMBL4294946)
Affinity DataKi:  2.60nMAssay Description:Inhibition of human CA9 assessed as enzyme inhibitor complex formation preincubated for 15 mins and measured for 10 to 100 secs by phenol red dye bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50465674(CHEMBL4294946)
Affinity DataKi:  7.80nMAssay Description:Inhibition of human CA12 assessed as enzyme inhibitor complex formation preincubated for 15 mins and measured for 10 to 100 secs by phenol red dye ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50465674(CHEMBL4294946)
Affinity DataKi:  2.08E+3nMAssay Description:Inhibition of human CA1 assessed as enzyme inhibitor complex formation preincubated for 15 mins and measured for 10 to 100 secs by phenol red dye bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50465674(CHEMBL4294946)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human CA2 assessed as enzyme inhibitor complex formation preincubated for 15 mins and measured for 10 to 100 secs by phenol red dye bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed